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    Baraban Lab
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Epilepsy Research Laboratory in the Department of Neurological Surgery

  • 37 CRISPR zebrafish models created
  • 4000+ drugs screened
  • 3 drugs in human clinical trials
  • 1 sea lion cured

 

 

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MGE

GABA interneurons, derived from embryonic medial ganglionic eminence (MGE), migrate, integrate, and functionally enhance inhibition following transplantation. We are developing MGE-based therapies.

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Zebrafish

Zebrafish offer significant advantages for in vivo functional analysis of gene function, high-throughput drug screening and whole-brain imaging of neural networks.  We pioneered a zebrafish-based platform for transformative epilepsy research & drug discovery.

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