Scott C. Baraban, PhD
Research Interests: epilepsy
I completed my undergraduate studies at Johns Hopkins University, and spent time in the laboratories of Elliott Blass (JHU), M. Flint Beal (Harvard) and Robert DeLorenzo (MCV) before entering the Pharmacology program at the University of Virginia. As a PhD student I studied the brainstem control of cardiorespiratory function with Patrice Guyenet and dentate granule cells with Eric Lothman. As a postdoctoral fellow in the laboratory of Phil Schwartzkroin (University of Washington) I worked on a variety of epilepsy related projects, including the role of NPY as an endogenous anticonvulsant peptide and animal models of malformation-related epilepsy. During these years I also worked with Richard Palmiter (HHMI) and Albert Berger (Dept. of Physiology). In 1999, I was recruited by Dr. Mitchell Berger to the Department of Neurological Surgery at the University of California, San Francisco and was named the William K. Bowes Jr. Endowed Chair in Neuroscience Research in 2008.
1984-1987: Johns Hopkins University (BA)
1990-1994: University of Virginia (PhD)
1997-1999 Assistant Professor, Department of Pediatrics, CWRU
1999-2003 Assistant Professor, Department of Neurological Surgery, UCSF
2003-2009 Assistant Professor, Department of Neurological Surgery, UCSF
2009- Professor, Department of Neurological Surgery, UCSF
2014-2015 Raymond & Beverly Sackler Sabbatical Fellow, UC Berkeley
2020- Adjunct Professor, Helen Wills Neuroscience Institute, UC Berkeley
1989 American Epilepsy Society & Milken Family Foundation, Postdoctoral Research Fellowship
1998 Epilepsy Foundation of America, Junior Investigator Research Award
1999 March of Dimes Foundation, Basil O’Connor Starter Scholar Award
1999 Sandler Family Supporting Foundation, UCSF Innovation in Basic Science Award
2003 Esther A. & Joseph Klingenstein Fund, Fellowship Award in the Neurosciences
2016 American Epilepsy Society, Research Recognition Award (Basic Science)
Dissociation of synchronization and excitability in furosemide blockade of epileptiform activity
Hochman DW, Baraban SC, Owens JW, Schwartzkroin PA
Science 1995 Oct 6;270(5233):99-102.
Knock-out mice reveal a critical epileptic role for neuropeptide Y
Baraban SC, Hollopeter G, Erickson JC, Schwartzkroin PA, Palmiter RD
Journal of Neuroscience 1997 Dec 1;17(23):8927-8936.
Pentylenetetrazole induced changes in zebrafish behavior, neural activity and c-fos expression
Baraban SC, Taylor MR, Castro PA, Baier H
Neuroscience 2005 131(3):759-768.
Cortical inhibition modified by embryonic neural precursors grafted into the postnatal brain
Alvarez-Dolado M, Calcagnotto ME, Karkar KM, Southwell DG, Jones-Davis DM, Estrada RC, Rubenstein JL, Alvarez-Buylla A, Baraban SC
Journal of Neuroscience 2006 Jul 12;26(28):7380-7389.
GABA progenitors grafted into the adult epileptic brain control seizures and abnormal behavior
Hunt RF, Girskis KM, Rubenstein JL, Alvarez-Buylla A, Baraban SC
Nature Neuroscience 2013 Jun 16;16(6):692-697.
Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment
Baraban SC, Dinday MT, Hortopan GA
Nature Communications 2013 4:2410.
Phenotypic analysis of catastrophic childhood epilepsy genes
Griffin A, Carpenter C, Liu J, Paterno R, Grone B, Hamling K, Moog M, Dinday MT, Figueroa F, Anvar M, Ononuju C, Qu T, Baraban SC
Communications Biology 2021 June 3;4(1):680.